• 来稿:陈琳   北京市虹天济神经科学研究院

  • Rinsho Shinkeigaku. 2003  Nov;43(11):824-6.   

  •  

  • Regeneration of central nervous system:  its concept and strategy

  •  

  • Okano H, Yoshizaki T, Okada  S.

  • Department of Physiology,  Keio  University School of  Medicine.

  •  

  • It had been long believed that our adult  mammalian central nervous system (CNS) does not regenerate after damage due to  injuries or degenerative diseases, as Santiago Ramóny Cajal had indicated long  time ago. Today, however, CNS came to be recognized as an important target of so  called "regenerative medicine". We have been proposing that regeneration of CNS  does include the following three concepts: i) re-growth of the damaged neuronal  axons, ii) replenishment of lost neural (or neuronal) cells and iii) recovery of  lost neural functions. Here, we would like to emphasize that to recapitulate  normal neural development is an essential strategy for CNS-regeneration. In this  review, we would like to take Parkinson's disease and spinal cord injury as  examples to discuss actual strategy aiming for CNS-regeneration.  

  •  


脊髓损伤的神经保护与神经再生策略
脊髓损伤后促进肌体积恢复的锻炼和移植机制

Previous:

Next:

中枢神经系统再生的概念与策略