• 来稿:陈琳   北京市虹天济神经科学研究院

  • C R Biol. 2006 Jul;329(7):465-75.   

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  • Neurogenesis in the adult central  nervous system

  • Taupin  P.

  • National Neuroscience Institute, Singapore, 11 Jalan Tan Tock Seng, Singapore 308433. obgpjt@nus.edu.sg

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  • Contrary to the long-held dogma,  neurogenesis occurs throughout adulthood, and neural stem cells reside in the  adult central nervous system (CNS) in mammals. The developmental process of the  brain may thus never end, and the brain may be amenable to repair. Neurogenesis  is modulated in a wide variety of physiological and pathological conditions, and  is involved in processes such as learning and memory and depression. However,  the relative contribution of newly generated neuronal cells to these processes,  as well as to CNS plasticity, remains to be determined. Thus, not only  neurogenesis contributes to reshaping the adult brain, it will ultimately lead  us to redefine our knowledge and understanding of the nervous  system.

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中枢神经系统中的神经元再生